17. AGA Clinical Practice Guideline on the Pharmacological Management of Irritable Bowel Syndrome With Diarrhea
CEUs: 2 Clinical
Average read time: 75 minutes.
Short Summary of the Article:
The article is an updated guideline from the American Gastroenterological Association (AGA) focusing on the pharmacological management of Irritable Bowel Syndrome with predominant diarrhea (IBS-D). It outlines various pharmacological agents like eluxadoline, rifaximin, alosetron, and others, reviewing their efficacy, dosage, and potential adverse effects. The guidelines are intended for clinicians and provide evidence-based recommendations using the GRADE framework
Learning Outcomes
Upon completion of this activity, you should have an understanding of:
- The key pharmacological treatments recommended for managing IBS-D and their clinical application.
- The risks and benefits associated with each treatment option, including potential adverse effects.
- How to apply shared decision-making principles in treating IBS-D patients, especially when conditional recommendations are present
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Earned Point(s): 0 of 0, (0) What is the primary treatment recommendation for patients with IBS-D? 2 Which antibiotic is commonly used in the treatment of IBS-D? 3 True or False: Rifaximin is recommended for long-term continuous use in IBS-D patients. 4 What is the recommended dosage of rifaximin for IBS-D patients? 4 Which of the following patients should avoid eluxadoline? 5 True or False: Alosetron is approved for use in all IBS-D patients regardless of severity. 6 Which therapy is conditionally recommended for women with severe IBS-D who have not responded to conventional treatments? 6 What is the primary concern associated with long-term use of loperamide in IBS-D? 7 Which drug class is NOT recommended for routine use in IBS-D patients? 8 True or False: Probiotics are strongly recommended as a primary treatment for IBS-D. 9 What is a key factor in deciding the pharmacological treatment for IBS-D? 10 Which non-pharmacological treatment is mentioned as beneficial in managing IBS-D? 11 Which of the following agents is NOT typically used in IBS-D treatment? 12 What is a common side effect of eluxadoline in IBS-D patients? 5 What is the first-line approach to managing mild IBS-D symptoms? 9
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