6, Advances in malaria pharmacology and the online guide to MALARIA PHARMACOLOGY: IUPHAR review
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Question 1 of 15
1. Question
What is the primary target of novel anti-malarial agents discussed in this article?
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pg 21
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Question 2 of 15
2. Question
Which mechanism is inhibited by compounds with a benzothiazole core scaffold?
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pg 22
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Question 3 of 15
3. Question
True or False: Proteasome inhibitors are ineffective in combating malaria.
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pg 21
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Question 4 of 15
4. Question
Which stage of the Plasmodium parasite life cycle is influenced by cGMP-dependent protein kinase?
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pg 22
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Question 5 of 15
5. Question
What is a key feature of UCT943, the next-generation PI4K inhibitor?
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pg 22
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Question 6 of 15
6. Question
True or False: Atovaquone resistance in Plasmodium parasites is linked to mutations in the parasite’s cytochrome b.
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pg 21
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Question 7 of 15
7. Question
Which of the following drugs targets malaria parasite histone deacetylases?
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pg 23
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Question 8 of 15
8. Question
What is the significance of Plasmodium phosphatidylinositol-4-kinase inhibitors?
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pg 24
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Question 9 of 15
9. Question
True or False: Malaria parasites resistant to atovaquone can still transmit via mosquitoes.
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pg 23
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Question 10 of 15
10. Question
What mechanism is affected by cytochrome bc1 inhibitors in malaria parasites?
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pg 21
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Question 11 of 15
11. Question
What is the potential impact of combining HDAC inhibitors with artemisinin?
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pg 24
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Question 12 of 15
12. Question
Which of the following malaria life cycle stages is the focus of PI4K inhibitors?
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pg 23
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Question 13 of 15
13. Question
What role does dihydroorotate dehydrogenase play in the malaria parasite?
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pg 21
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Question 14 of 15
14. Question
Which strategy is used to prevent malaria transmission by mosquitoes?
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pg 22
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Question 15 of 15
15. Question
What is the mechanism of action of proteasome inhibitors in malaria treatment?
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pg 21
